Rejuran Skin Booster in Bangkok: The Complete Guide (2026)

What Is the Rejuran Skin Booster?

Rejuran is a premium injectable skin booster containing Polynucleotide (PN), extracted from salmon DNA. It works at the cellular level to repair damaged skin, stimulate collagen production, and improve overall skin health. Unlike dermal fillers or Botox, Rejuran focuses on long-term skin regeneration rather than temporary cosmetic enhancement.

Developed by PharmaResearch, a Korean pharmaceutical company approved by the Korean FDA, Rejuran uses salmon DNA with a molecular structure remarkably similar to human DNA. This makes it highly biocompatible with minimal risk of allergic reactions. When injected into the dermis, PN fragments activate your skin's natural repair mechanisms—stimulating fibroblast growth, collagen production, and anti-inflammatory responses.

Rejuran Lineup: Which One Is Right for You?

Rejuran isn't just one product—it's a family of four specialized formulas, each engineered for different skin concerns. At Edition Clinic, we offer all four types so your doctor can select the most effective formula for your skin.

Image: Rejuran product lineup by PharmaResearch

Rejuran Healer (Black Box) — The All-Rounder

Rejuran Healer is the original and most popular formula in the Rejuran lineup. It contains high-purity Polynucleotide (PN) in a 2cc vial—the largest volume per vial, making it the most cost-effective option for treating larger areas. Rejuran Healer is ideal for full face rejuvenation, improving fine lines, boosting elasticity, and enhancing overall skin quality.

Rejuran HB (Red Box) — Hydration + Regeneration

Rejuran HB combines PN with Hyaluronic Acid (HA) and Lidocaine in a 1cc vial. The added HA delivers immediate deep hydration alongside regeneration, while Lidocaine significantly reduces pain during injection. This makes Rejuran HB an excellent choice for first-time patients, those with dry or dehydrated skin, or anyone who prefers a more comfortable treatment experience. A recent study published in PubMed confirmed that combining PN with HA synergistically accelerates wound healing and tissue remodeling.

Rejuran S (Blue Box) — Scar Specialist

Rejuran S features a high-concentration, high-viscosity PN formula in a 1cc vial, specifically engineered for acne scars and deep textural damage. It is injected directly under depressed scars to promote collagen rebuilding and tissue reconstruction from within. Due to its thicker consistency, Rejuran S uses a slightly larger needle (30G) and may cause more pronounced papules than other formulas, but it delivers the strongest regenerative power for scar repair.

Rejuran I (White Box) — Under-Eye Specialist

Rejuran I is a low-viscosity PN formula in a 1cc vial, designed specifically for the thin, delicate skin around the eyes. Its fluid consistency prevents lumps or bumps in this sensitive area while still delivering effective regeneration. Rejuran I is particularly effective for dark circles, crow's feet, under-eye fine lines, and crepey texture. Clinical research has shown PN-based treatments to significantly improve skin elasticity and hydration in treated areas.

Rejuran Pricing at Edition Clinic Bangkok

All four Rejuran formulas are available at the same price. Purchase 2 or more vials and receive a 10% discount. We recommend only the minimum necessary treatment—no overselling.

Price Per Vial

Rejuran Healer: Recommended Treatment Volume

Rejuran Healer comes in 2cc vials, making it the most cost-effective option for larger treatment areas:

• 1 Vial (2cc) — Targeted: Under-eye or specific area. 9,000 THB.
• 2 Vials (4cc) — Most Popular: Full face coverage. 18,000 THB 16,200 THB (10% off).
• 3 Vials (6cc) — Comprehensive: Full face + neck. 27,000 THB 24,300 THB (10% off).

*Most clients benefit from 3–4 sessions spaced 3–4 weeks apart. 10% discount applies to 2+ vials purchased in a single session. Final treatment plan confirmed after consultation. All prices include consultation, numbing cream, LDM therapy, and modeling pack.

Why Choose Edition Clinic for Rejuran?

Edition Clinic is a Korean-standard aesthetic clinic in Thonglor, Bangkok, operating under a Seoul Gangnam clinic partnership. We don't just inject Rejuran—we design your skin regeneration journey with medical precision and honest care.

Korean-Standard Protocols

Through our partnership with a Seoul Gangnam clinic, our medical team follows Korean injection protocols with continuous training updates. You receive the same treatment standards as premium Seoul clinics—right here in Bangkok.

Doctor-Performed Injection

Every Rejuran injection at Edition Clinic is performed by experienced physicians—never delegated to nurses or technicians. With a medical team that has 16+ years of combined experience, every shot is placed with precision for optimal results.

100% Authentic Product

Genuine Rejuran is opened and verified in front of you with QR code verification before every injection. Full transparency guaranteed—no imitations, no dilution.

Honest Treatment Plans

We recommend only the minimum necessary treatment to achieve your goals. Our medical team (16+ years experience) will give you honest advice—including if a different treatment would work better for you. No overselling, no unnecessary add-ons.

Before & After Results

*Results may vary. Individual results are not guaranteed. All treatments performed by licensed medical professionals.

How Does Rejuran Healer Work?

Rejuran works by delivering Polynucleotide (PN) directly into the dermis, where it provides the building blocks for DNA synthesis and enables damaged skin cells to repair themselves. According to clinical research published in PubMed, intradermal PN treatment leads to statistically significant improvement in skin surface, firmness, pigmentation, and radiance. PN thickens the dermis, improves elasticity, and strengthens the skin's protective barrier, while its anti-inflammatory properties reduce redness and normalize sebum production.

Cellular Regeneration & Repair

PN fragments activate fibroblasts—the cells responsible for producing collagen, elastin, and other structural proteins. Once activated, fibroblasts increase production of new collagen fibers, strengthening the skin's structural framework. This process also accelerates the turnover of damaged cells, replacing them with healthy new tissue. The result is visibly firmer, smoother skin with improved texture over time.

Anti-Inflammatory Action

PN has natural anti-inflammatory properties that help calm irritated or reactive skin. It reduces the production of pro-inflammatory cytokines while promoting healing factors. This makes Rejuran particularly beneficial for patients with rosacea, chronic redness, post-acne inflammation, or compromised skin barriers.

Angiogenesis (New Blood Vessel Formation)

Rejuran stimulates the formation of new micro-blood vessels in the treatment area. Improved blood circulation means better delivery of oxygen and nutrients to skin cells, and more efficient removal of waste products. This enhanced blood supply contributes to a healthier, more radiant complexion—the "Rejuran glow" that patients notice within the first week after treatment.

Growth Factor Stimulation

PN triggers the release of multiple growth factors including VEGF (Vascular Endothelial Growth Factor) and FGF (Fibroblast Growth Factor). These growth factors create a cascade effect—each activated cell signals neighboring cells to begin repair and regeneration. This is why Rejuran's effects continue to develop for weeks after injection.

Moisture Retention Enhancement

By strengthening the skin barrier and improving dermal structure, Rejuran enhances your skin's natural ability to retain moisture. Unlike topical moisturizers that sit on the surface, Rejuran works from within to restore the skin's hydration capacity. Patients often find their existing skincare products become more effective after Rejuran treatment.

What Are the Benefits of Rejuran?

Rejuran offers comprehensive skin improvements that address both visible concerns and underlying skin health. In our clinical practice, we've observed that patients who complete the full 3–4 session course consistently report the most dramatic and long-lasting improvements.

• Repairs damaged skin and improves overall texture
• Reduces fine lines, wrinkles, and acne scars
• Tightens pores and normalizes oil production
• Enhances skin elasticity and firmness
• Provides long-lasting hydration and a natural glow
• Strengthens the skin barrier against environmental damage
• Calms inflammation and reduces redness

Ideal Candidates for Rejuran

Rejuran is suitable for anyone looking to improve their skin health. It is especially beneficial for:

• Dehydrated, Dull Skin: If your skin looks tired, lacks radiance, or feels chronically dry despite using moisturizers, Rejuran can restore that healthy glow from within.
• Damaged Skin Barrier: Patients with compromised skin barriers (often from over-exfoliation, harsh products, or environmental damage) benefit significantly from Rejuran's barrier-repairing properties.
• Acne Scars & Textural Irregularities: Rejuran S is specifically designed for this concern—one of the most effective non-ablative treatments for improving atrophic acne scars.
• Sensitive, Reactive Skin: The anti-inflammatory properties make Rejuran ideal for patients with rosacea or chronic redness.
• Early Signs of Aging: Fine lines, loss of elasticity, and decreased radiance respond excellently to Rejuran.
• Post-Procedure Healing: Rejuran accelerates healing after laser resurfacing, chemical peels, or microneedling.
• Preventative Anti-Aging: Younger patients (25–35) can use Rejuran proactively to maintain skin quality.

Who Should Avoid Rejuran?

While Rejuran is safe for most people, it is not recommended for pregnant or breastfeeding women, those with active skin infections at the treatment site, patients with known allergies to fish or salmon-derived products, or individuals on blood-thinning medications (consult your doctor first).

Where Can Rejuran Be Applied?

Rejuran can be applied to multiple areas of the face and body. The specific formula, volume, and injection technique are customized based on the treatment area.

Full Face

Full face treatment is the most common approach, using Rejuran Healer (1–2 vials) to address overall skin quality. The doctor performs micro-injections across the forehead, cheeks, temples, chin, and jawline to deliver comprehensive regeneration.

Targeted Facial Zones

For specific concerns, your doctor may focus Rejuran on targeted areas. The cheeks respond well to pore tightening and texture improvement. The forehead benefits from treatment for fine lines. The perioral area can be treated for smoker's lines and nasolabial fold improvement.

Under-Eye Area

The delicate under-eye area requires special attention. Rejuran I was specifically developed for this zone, with a lower viscosity that prevents lumps in thin skin. It effectively addresses dark circles, crow's feet, and crepey texture.

Neck & Décolletage

The neck ages faster than the face due to thinner skin and greater sun exposure. Rejuran Healer can improve crepey texture and horizontal neck lines. Neck treatment typically requires 1–2 additional vials beyond the face.

What Does a Rejuran Treatment Session Look Like?

At Edition Clinic, we follow a structured 4-step protocol to ensure optimal results. Each session takes approximately 60 minutes from start to finish.

Step 1: Consultation & Assessment (5–10 min)

Your doctor evaluates your skin condition, discusses your concerns, and designs a customized injection plan. This includes selecting the right Rejuran formula and determining the optimal injection volume and technique.

Step 2: Numbing Cream Application (20–30 min)

A topical anesthetic cream is applied generously. We allow a full 20–30 minutes for the numbing to take full effect, ensuring maximum comfort during injection.

Step 3: Rejuran Injection (20–30 min)

The doctor performs precise micro-injections at controlled depth. The authentic Rejuran product is opened and verified in front of you before injection. You may feel mild pressure, but significant pain is rare with proper numbing.

Step 4: Post-Treatment Care (10–15 min)

We apply complimentary LDM (Local Dynamic Micro-massage) ultrasound therapy to enhance product absorption and accelerate healing. This is followed by a professional modeling pack for soothing and deep hydration. Post-care instructions are provided before you leave.

Recommended Treatment Course

We recommend 3–4 sessions spaced 3–4 weeks apart for optimal results. Each session builds upon the previous one:

• Session 1: Establishes the foundation. Improved hydration and a subtle glow within 5–7 days.
• Session 2: Amplifies results. Texture improvements become more noticeable.
• Session 3: Significant improvements in skin quality, elasticity, and tone.
• Session 4: Consolidates results for stable, long-lasting improvement.

After completing your initial course, maintenance sessions every 6 months help sustain results.

Rejuran Results: What to Expect Week by Week

Results from Rejuran are gradual and progressive. Unlike fillers that show instant results, Rejuran works by stimulating your body's natural regeneration—so improvements develop over weeks.

Week 1: Immediate Post-Treatment

Small bumps (papules) at injection sites are visible for 1–3 days—completely normal. Mild redness and swelling may occur but typically subsides within 24–48 hours.

Days 5–7: Initial Hydration Phase

The first visible improvement appears—your skin takes on a subtle, healthy glow. Hydration levels improve as the PN begins integrating into the dermis. Many patients describe their skin as feeling "plumper" and more supple.

Weeks 2–4: Progressive Improvement

Collagen stimulation begins in earnest. Skin texture refines, pores appear smaller, and fine lines begin to soften. By week 3–4, most patients notice significant changes in elasticity and radiance. This is when you're due for your next session.

After Full Course (Sessions 3–4): Peak Results

After completing the full treatment course, you'll see the cumulative effect. Patients typically report visibly firmer, more radiant skin with reduced fine lines, improved pore size, and enhanced elasticity.

Months 3–6+: Sustained Results & Maintenance

Rejuran's regenerative effects continue working after your last session. Results typically remain stable for 4–6 months. A single maintenance session every 6 months helps preserve improvements. Patients who maintain consistent sessions often report that their skin quality improves year over year.

Rejuran vs. Other Skin Booster Treatments

Edition Clinic offers a comprehensive range of skin rejuvenation treatments. Understanding how Rejuran compares helps you choose the right treatment—or combination—for your goals.

Rejuran vs Profhilo

Rejuran and Profhilo are both excellent injectable treatments, but they work through different mechanisms. Rejuran uses polynucleotides to heal and regenerate damaged skin at a cellular level—superior for acne scars, damaged barriers, and sensitivity. Profhilo uses ultra-high concentration hyaluronic acid for bio-remodeling, excelling at improving elasticity and overall anti-aging with minimal downtime. Many patients combine both for comprehensive results.

Rejuran vs Sculptra

Sculptra uses PLLA to stimulate deep collagen production and restore facial volume. Results can last 2+ years. If your primary concern is volume loss, Sculptra is more appropriate. If your concern is skin quality, texture, or damage, Rejuran is the better choice.

Rejuran vs Juvelook

Juvelook combines PDLLA with non-crosslinked HA for pore tightening and texture refinement. While both address textural concerns, Rejuran focuses on healing through polynucleotides—making it superior for damaged, sensitive, or compromised skin. Juvelook is more targeted for pore reduction.

Rejuran vs Exosome

Both are regenerative treatments. Exosome tends to work faster and is excellent for advanced anti-aging. Rejuran has a longer track record, more clinical data, and is particularly effective for acne scars and barrier repair. Some patients alternate between the two for comprehensive regenerative benefits.

Is Rejuran Safe? Side Effects & Aftercare

Rejuran is very safe when administered by a qualified doctor. Polynucleotide is biocompatible and hypoallergenic, suitable for even sensitive skin types. According to published research, PDRN/PN has demonstrated an excellent safety profile across multiple clinical trials with no serious adverse effects. All treatments at Edition Clinic are performed by licensed medical professionals.

Normal Post-Treatment Reactions

The following are completely normal and expected: small papules (bumps) at injection sites resolving within 1–5 days, mild redness fading within a few hours, slight swelling subsiding within 24–48 hours, and minor tenderness at the injection area.

Possible Side Effects

Uncommon but possible side effects include bruising (more likely with blood-thinning medications), prolonged swelling beyond 48 hours (more common with Rejuran HB due to the HA component), and temporary itching. Serious complications are extremely rare when treatment is performed by a qualified physician using authentic products.

Aftercare: First 6 Hours

Keep the treated area completely clean and untouched. No makeup, skincare products, or face washing. Resist the urge to touch or press the bumps—they will resolve on their own.

Aftercare: First 24–48 Hours

Use lukewarm water and a mild, fragrance-free cleanser for gentle washing only. Avoid heat exposure including saunas, steam rooms, and hot yoga. Skip strenuous exercise. Sleep with an extra pillow to minimize swelling.

Aftercare: First Week

Wear SPF 50+ sunscreen daily. Use only mild, non-irritating skincare products—avoid acids, retinoids, and exfoliants. Drink plenty of water. Skip facials, peels, or other aesthetic procedures.

Long-Term Care

Maintain a quality skincare routine with moisturizers and sunscreen. Attend all scheduled sessions for optimal cumulative results. Schedule maintenance sessions every 6 months.

Frequently Asked Questions About Rejuran

1. What is the difference between Rejuran Healer, HB, S, and I?

Answer: Rejuran Healer (Black box, 2cc) is the original formula for overall skin regeneration and anti-aging. Rejuran HB (Red box, 1cc) combines PN with Hyaluronic Acid and Lidocaine for hydration plus regeneration with less pain—ideal for first-timers. Rejuran S (Blue box, 1cc) is a high-viscosity formula designed for acne scars and deep textural damage. Rejuran I (White box, 1cc) is a low-viscosity formula for the delicate under-eye area. All are 9,000 THB per vial at Edition Clinic.

2. When will I see results from Rejuran?

Answer: You'll notice improved hydration and radiance within 5–7 days after your first session. More significant improvements in texture, elasticity, and skin quality become visible at 2–4 weeks. Peak results appear after completing your full course (3–4 sessions).

3. How much does Rejuran cost in Bangkok?

Answer: At Edition Clinic, all Rejuran products are 9,000 THB per vial. Purchase 2 or more vials in a single session for a 10% discount (e.g., 2 vials = 16,200 THB). Every treatment includes complimentary LDM therapy (worth 1,999 THB) and a modeling pack (worth 999 THB).

4. How many sessions do I need?

Answer: We recommend 3–4 sessions spaced 3–4 weeks apart for optimal results. Results build progressively with each session.

5. Is Rejuran painful?

Answer: With numbing cream applied for 20–30 minutes before treatment, discomfort is minimal. Rejuran HB contains Lidocaine which further reduces pain—a good choice for first-time patients or those sensitive to pain.

6. What about the bumps after treatment?

Answer: The small bumps (papules) at injection sites are completely normal. The product sits at these points before gradually distributing and activating regeneration. Bumps typically disappear within 24–48 hours, occasionally up to 5–7 days.

7. Can I wear makeup after treatment?

Answer: Wait at least 6 hours before applying makeup. Most patients can resume makeup the next day. Use clean brushes and gentle products for the first few days.

8. How long do results last?

Answer: Results typically last 4–6 months after completing a full course. Maintenance sessions every 6 months sustain results long-term.

9. Can I combine Rejuran with other treatments?

Answer: Absolutely! Rejuran works well with Profhilo (bio-remodeling), Sculptra (volume), Botox (wrinkle prevention), and Potenza RF microneedling (acne scars). Space treatments 2–4 weeks apart.

10. Is Rejuran better than Profhilo?

Answer: They serve different purposes. Rejuran excels at healing damaged skin, improving acne scars, and repairing barriers. Profhilo excels at bio-remodeling, elasticity, and overall anti-aging. Many patients benefit from both.

11. Will Rejuran help with acne scars?

Answer: Yes! Rejuran S is specifically designed for acne scars. For deeper scars, combining Rejuran S with Potenza RF microneedling delivers excellent results.

12. I have sensitive skin—is Rejuran safe for me?

Answer: Rejuran is actually ideal for sensitive skin. Its anti-inflammatory properties calm reactive skin, reduce redness, and strengthen the barrier. Many patients with rosacea find Rejuran transformative.

13. Which Rejuran should I choose?

Answer: Healer for overall anti-aging (best all-rounder). HB for hydration with less pain (great for first-timers). S for acne scars and deep damage. I for under-eye concerns. Your doctor will recommend the best option during your free consultation.

14. What are LDM and modeling pack included with Rejuran?

Answer: Every Rejuran treatment includes two complimentary post-treatment services. LDM (Local Dynamic Micro-massage) is an ultrasound therapy that enhances absorption and healing (valued at 1,999 THB). The modeling pack provides deep hydration and calms the skin (valued at 999 THB).

15. Can younger patients get Rejuran?

Answer: Yes! Rejuran is excellent for preventative anti-aging in patients as young as mid-20s. It helps maintain skin health and address early concerns like dehydration, dullness, or minor texture issues.